Research/Clinical Trials

Explore the latest breakthroughs in clinical research and trials. Stay informed about innovative treatments and scientific discoveries shaping the future of medicine.

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T1D Guide T1D Strong News Personal Stories Resources T1D Misdiagnosis T1D Early Detection Research/Clinical Trials

Tzield Just Approved for Ages 1 and Up in Stage 2 T1D

Erin Poche

April 26, 2026

Erin Poche

May 4, 2026

T1D Guide T1D Strong News Personal Stories Resources T1D Misdiagnosis T1D Early Detection Research/Clinical Trials

Type 1 Diabetes Breakthroughs to Watch in 2026

Erin Poche

April 19, 2026

Erin Poche

April 21, 2026

T1D Guide T1D Strong News Personal Stories Resources T1D Misdiagnosis T1D Early Detection Research/Clinical Trials

From Screening Her Children to Starting Tzield: Chris Dunn’s Type 1 Diabetes Journey

Erin Poche

March 16, 2026

Erin Poche

May 18, 2026

T1D Guide T1D Strong News Personal Stories Resources T1D Misdiagnosis T1D Early Detection Research/Clinical Trials

Think Like a Pancreas: Gary Scheiner on Type 1 Diabetes Education and Living Well

Kelly Dawes

February 22, 2026

Kelly Dawes

February 20, 2026

T1D Guide T1D Strong News Personal Stories Resources T1D Misdiagnosis T1D Early Detection Research/Clinical Trials

Tegoprubart is a Game Changer in Islet Cell Transplantation Surgery for T1D Patients

Erin Poche

February 9, 2026

Erin Poche

February 9, 2026

T1D Guide T1D Strong News Personal Stories Resources T1D Misdiagnosis T1D Early Detection Research/Clinical Trials

Type 1 Diabetes in 2025: Advances in Early Detection, Screening, and What’s Next

Kelly Dawes

January 12, 2026

Kelly Dawes

January 12, 2026

T1D Guide T1D Strong News Personal Stories Resources T1D Misdiagnosis T1D Early Detection Research/Clinical Trials

Inside the Chicago Diabetes Project: Executive Director Jill Dine on the Search for a T1D Cure

Erin Poche

December 13, 2025

Erin Poche

January 8, 2026

T1D Guide T1D Strong News Personal Stories Resources T1D Misdiagnosis T1D Early Detection Research/Clinical Trials

Baricitinib’s Breakthrough and Why Screening for T1D Matters More Than Ever

Erin Poche

December 7, 2025

Erin Poche

December 8, 2025

T1D Guide T1D Strong News Personal Stories Resources T1D Misdiagnosis T1D Early Detection Research/Clinical Trials

Catching Type 1 Early: A Mom’s Journey Through Screening and Tzield Therapy

Julia Flaherty

October 27, 2025

Julia Flaherty

October 24, 2025

T1D Guide T1D Strong News Personal Stories Resources T1D Misdiagnosis T1D Early Detection Research/Clinical Trials

Why More Families Are Screening Their Children for Type 1 Diabetes—Two Stories with Different Outcomes

Erin Poche

October 20, 2025

Erin Poche

January 8, 2026

T1D Guide T1D Strong News Personal Stories Resources T1D Misdiagnosis T1D Early Detection Research/Clinical Trials

COUR Pharma Pursues Disease-Modifying Therapy for T1D

Erin Poche

October 6, 2025

Erin Poche

October 3, 2025

T1D Guide T1D Strong News Personal Stories Resources T1D Misdiagnosis T1D Early Detection Research/Clinical Trials

What Causes Type 1 Diabetes: Your Beta Cells or Immune System?

Ginger Vieira

October 5, 2025

Ginger Vieira

October 3, 2025

T1D Guide T1D Strong News Personal Stories Resources T1D Misdiagnosis T1D Early Detection Research/Clinical Trials

Doctors at UI Health Performed the First Islet Transplant with Lantidra

Erin Poche

September 28, 2025

Erin Poche

December 8, 2025

T1D Guide T1D Strong News Personal Stories Resources T1D Misdiagnosis T1D Early Detection Research/Clinical Trials

Top Type 1 Diabetes Research Breakthroughs to Watch in 2025

Erin Poche

September 23, 2025

Erin Poche

September 29, 2025

T1D Guide T1D Strong News Personal Stories Resources T1D Misdiagnosis T1D Early Detection Research/Clinical Trials

Zucara’s New Drug Aims to Prevent Overnight Lows in Type 1 Diabetes

Ginger Vieira

September 14, 2025

Ginger Vieira

September 15, 2025

T1D Guide T1D Strong News Personal Stories Resources T1D Misdiagnosis T1D Early Detection Research/Clinical Trials

Diabetes Research Connection Launches 2025 Funding Opportunities for Early-Career Type 1 Diabetes Scientists

Kelly Dawes

August 31, 2025

Kelly Dawes

September 2, 2025

T1D Guide T1D Strong News Personal Stories Resources T1D Misdiagnosis T1D Early Detection Research/Clinical Trials

T1D Cure Research Breakthroughs from Vertex and Sana Biotechnology

Ginger Vieira

June 29, 2025

Ginger Vieira

June 30, 2025

T1D Guide T1D Strong News Personal Stories Resources T1D Misdiagnosis T1D Early Detection Research/Clinical Trials

TrialNet Helps Delay the Progression of Type 1 Diabetes

Julia Flaherty

April 28, 2025

Julia Flaherty

January 8, 2026

T1D Guide T1D Strong News Personal Stories Resources T1D Misdiagnosis T1D Early Detection Research/Clinical Trials

Vertex’s VX-264 Clinical Trial Fails to Produce Results & Ends Abruptly

Ginger Vieira

April 6, 2025

Ginger Vieira

June 30, 2025

T1D Guide T1D Strong News Personal Stories Resources T1D Misdiagnosis T1D Early Detection Research/Clinical Trials

New Disease-Modifying Therapies that Delay T1D Onset

Erin Poche

March 24, 2025

Erin Poche

March 24, 2025

T1D Guide T1D Strong News Personal Stories Resources T1D Misdiagnosis T1D Early Detection Research/Clinical Trials

Research in China is Curing Type 1 Diabetes with Fat Cells

Tara Mayo

March 15, 2025

Tara Mayo

March 21, 2025

T1D Guide T1D Strong News Personal Stories Resources T1D Misdiagnosis T1D Early Detection Research/Clinical Trials

Denosumab: Another Reason to Screen for T1D

Erin Poche

February 15, 2025

Erin Poche

March 21, 2025

T1D Guide T1D Strong News Personal Stories Resources T1D Misdiagnosis T1D Early Detection Research/Clinical Trials

Sana Biotech’s Cell Therapy without Immunosuppression is a Gamechanger

Erin Poche

January 26, 2025

Erin Poche

June 30, 2025

T1D Guide T1D Strong News Personal Stories Resources T1D Misdiagnosis T1D Early Detection Research/Clinical Trials

Will These Scientists and Their Cows Help Cure Type 1 Diabetes?

Ginger Vieira

January 19, 2025

Ginger Vieira

March 25, 2025

T1D Guide T1D Strong News Personal Stories Resources T1D Misdiagnosis T1D Early Detection Research/Clinical Trials

Vertex T1D Trial VX-880 Moves into Phase III

Erin Poche

December 1, 2024

Erin Poche

June 30, 2025

T1D Guide T1D Strong News Personal Stories Resources T1D Misdiagnosis T1D Early Detection Research/Clinical Trials

First T1D Functional Cure Using Immunosuppressive Therapy

Erin Poche

November 10, 2024

Erin Poche

March 25, 2025

T1D Guide T1D Strong News Personal Stories Resources T1D Misdiagnosis T1D Early Detection Research/Clinical Trials

Stem Cell Therapy to Reverse T1D Inspires Hope

Erin Poche

November 4, 2024

Erin Poche

March 25, 2025

T1D Guide T1D Strong News Personal Stories Resources T1D Misdiagnosis T1D Early Detection Research/Clinical Trials

Diamyd Medical has a Clinical Trial for Newly Diagnosed T1Ds

Ginger Vieira

October 27, 2024

Ginger Vieira

March 25, 2025

T1D Guide T1D Strong News Personal Stories Resources T1D Misdiagnosis T1D Early Detection Research/Clinical Trials

T1D Human Trials Happening Right Now

Erin Poche

September 1, 2024

Erin Poche

March 26, 2025

T1D Guide T1D Strong News Personal Stories Resources T1D Misdiagnosis T1D Early Detection Research/Clinical Trials

Vertex Pharmaceuticals Seeks Solutions to Cure T1D

Erin Poche

January 28, 2024

Erin Poche

September 29, 2025

T1D Guide T1D Strong News Personal Stories Resources T1D Misdiagnosis T1D Early Detection Research/Clinical Trials

Interview with Breakthrough T1D (Formerly JDRF) Market Director, Mike Somers

T1D Team

November 22, 2023

T1D Team

March 27, 2025

T1D Guide T1D Strong News Personal Stories Resources T1D Misdiagnosis T1D Early Detection Research/Clinical Trials

Lantidra: A Possible Cure for TID?

Erin Poche

October 24, 2023

Erin Poche

March 27, 2025

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Three Months Later: Katie Beth Hand's Life After Becoming Insulin-Independent in the Eledon Trial

Three months ago, Katie Beth Hand was cautiously optimistic. The Arkansas mother of four had recently become one of the first participants in an investigator-led study at UChicago Medicine combining transplanted donor islet cells with Eledon's investigational anti-CD40L therapy, tegoprubart.

Ginger Vieira

June 22, 2026

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Father and Son Paul and Nick Peloso Discuss Growing Up with Type 1 Diabetes and the Breakthrough T1D Therapy Paul Is Developing

Paul Peloso, MD, is the chief medical officer (CMO) at COUR Pharmaceuticals, a clinical-stage biotech company developing a promising disease-modifying therapy for type 1 diabetes (T1D). His son, Nick, has type 1, which makes Paul’s commitment even stronger.

Erin Poche

June 15, 2026

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Highlights, Controversy, and Celebration at the ADA’s 86th Scientific Sessions

This year’s American Diabetes Association (ADA) 86th Scientific Sessions, held in New Orleans, Louisiana, did not disappoint, bringing together more than 12,000 researchers, industry leaders, scientists, and healthcare professionals from around the world to share the latest breakthroughs in diabetes care.

Erin Poche

June 13, 2026

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Tzield Just Approved for Ages 1 and Up in Stage 2 T1D

In a significant new development, the U.S. Food and Drug Administration (FDA) has approved Sanofi’s Tzield (teplizumab-mzwv) for toddlers with stage 2 type 1 diabetes (T1D), making it the first disease-modifying therapy available for children aged one and older at this stage.

Erin Poche

April 26, 2026

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Type 1 Diabetes Breakthroughs to Watch in 2026

2026 brings major breakthroughs for people living with type 1 diabetes (T1D). Here, we highlight new discoveries focusing on stem cell-derived islet replacements, targeted immunosuppression therapies, encapsulation technology and hypoimmune therapies in the works.

Erin Poche

April 19, 2026

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From Screening Her Children to Starting Tzield: Chris Dunn’s Type 1 Diabetes Journey

Chris Dunn is no stranger to type 1 diabetes (T1D). Her son Nolan was diagnosed at two years old, and her daughter, Patsy, followed at age four. Having two young children with type 1 is hard for many to imagine. It’s the reason many parents push the idea of screening aside, but Dunn said it was the best decision she’s ever made. Through early detection, she discovered she carries T1D autoantibodies and has started Tzield, a disease-modifying therapy, to delay onset.

Erin Poche

March 16, 2026

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Think Like a Pancreas: Gary Scheiner on Type 1 Diabetes Education and Living Well

Living well with type one diabetes (T1D) is not about perfect numbers. For decades, Gary Scheiner has helped shape how people understand insulin, manage glucose and set realistic expectations. Drawing on lived experience, clinical training, and a deep commitment to people living with diabetes, Scheiner has built a career rooted in practical guidance, compassionate care, and the belief that no one should have to figure out this condition alone.

Kelly Dawes

February 22, 2026

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Tegoprubart is a Game Changer in Islet Cell Transplantation Surgery for T1D Patients

A new immunosuppressant medication for islet cell transplant surgeries is reshaping the future of transplantation for people with type 1 diabetes (T1D). The drug tegoprubart has so far shown no serious side effects, unlike other immunosuppressants. In 2025, this combined drug-and-surgery approach is demonstrating promising success in the path to a cure.

Erin Poche

February 9, 2026

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Type 1 Diabetes in 2025: Advances in Early Detection, Screening, and What’s Next

From expanded type 1 diabetes (T1D) screening programs to therapies designed to work earlier in the disease process, 2025 marked a clear inflection point in how T1D is identified and discussed. Growing attention to early detection has moved the conversation beyond diagnosis alone toward earlier risk identification, reduced medical emergencies, and improved long-term outcomes.

Kelly Dawes

January 12, 2026

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Inside the Chicago Diabetes Project: Executive Director Jill Dine on the Search for a T1D Cure

When Chicago native Jill Dine’s son was diagnosed with type 1 at two years old, she and her husband began searching for ways to get involved with the T1D community. They didn’t have to look far — the Chicago Diabetes Project, a world-renowned organization leading advancements in gene therapies, islet transplants, and functional cure research, was already thriving in their hometown.

Erin Poche

December 13, 2025

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Baricitinib’s Breakthrough and Why Screening for T1D Matters More Than Ever

One of the most powerful reasons to screen for type 1 diabetes (T1D) is the ability of disease-modifying therapies, like Tzield (teplizumab) and Baricitinib, to delay the disease’s progression. A groundbreaking study by Australian researchers found that a daily pill containing the JAK inhibitor baricitinib helps preserve insulin production in newly diagnosed individuals with T1D.

Erin Poche

December 7, 2025

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Catching Type 1 Early: A Mom’s Journey Through Screening and Tzield Therapy

For many families, a diagnosis of type 1 diabetes (T1D) often comes as a crisis. Fortunately, Stephanie’s family had a different experience. One summer, after her oldest daughter returned home from her first year of college, she mentioned feeling shaky before mealtimes. At first, it seemed like a typical case of freshman nutrition—or lack thereof. Stephanie suggested that her daughter increase her protein intake and reduce her consumption of cafeteria carbs. Then, the campus health center called with lab results that revealed a different story.

Julia Flaherty

October 27, 2025

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Why More Families Are Screening Their Children for Type 1 Diabetes—Two Stories with Different Outcomes

We know type 1 diabetes has a genetic component, with siblings having a 15 times higher risk. We also know that early detection can prevent dangerous emergencies and that screening opens the door to preventive trials. The question remains, why isn’t type 1 screening standard practice for kids at risk?

Erin Poche

October 20, 2025

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COUR Pharma Pursues Disease-Modifying Therapy for T1D

COUR Pharma’s CNP-103 is a first-of-its-kind tolerogenic therapy designed to retrain the immune system in newly diagnosed type 1 diabetes—stopping islet cell destruction, preserving insulin, and potentially reversing abnormal glucose levels. T1D Strong spoke with Chief Medical Officer, Dr. Paul Peloso, about this groundbreaking approach.

Erin Poche

October 6, 2025

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What Causes Type 1 Diabetes: Your Beta Cells or Immune System?

At the onset of type 1 diabetes, it’s easy to joke about “needing a new pancreas” or to feel frustrated with our dysfunctional immune system attacking things it shouldn’t. But what if the cells in your pancreas that produce insulin are actually guilty of inviting the attack?

Ginger Vieira

October 5, 2025

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Doctors at UI Health Performed the First Islet Transplant with Lantidra

On August 26, 2025, a 69-year-old man, Edward Augustin III, from Illinois, received the first islet cell transplant with Lantidra, an FDA-approved cell therapy that utilizes donor pancreatic islet cells. Within one week, he was able to stop taking daily insulin injections.

Erin Poche

September 28, 2025

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Top Type 1 Diabetes Research Breakthroughs to Watch in 2025

Over the last twenty years, as technology has advanced at lightning speed, the T1D community has undergone its own transformation, with digital health and cutting-edge research driving remarkable diabetes breakthroughs.

Erin Poche

September 23, 2025

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Zucara’s New Drug Aims to Prevent Overnight Lows in Type 1 Diabetes

For anyone living with type 1 diabetes, low blood sugars are easily one of the scariest and most exhausting parts of the condition. Hypoglycemia is unpredictable, disruptive, and dangerous — especially when it happens in the middle of the night.

Ginger Vieira

September 14, 2025

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Diabetes Research Connection Launches 2025 Funding Opportunities for Early-Career Type 1 Diabetes Scientists

Big ideas need early support. The Diabetes Research Connection (DRC) is opening its second funding round of 2025 to back fresh breakthroughs in type 1 diabetes (T1D). Through peer‑reviewed seed grants of up to $75,000, DRC empowers early‑career scientists to prevent, treat, and improve life with T1D.

Kelly Dawes

August 31, 2025

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T1D Cure Research Breakthroughs from Vertex and Sana Biotechnology

Two major announcements captured the spotlight at last week’s American Diabetes Association 85th Scientific Sessions, signaling exciting progress in cell therapy for type 1 diabetes.

Ginger Vieira

June 29, 2025

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TrialNet Helps Delay the Progression of Type 1 Diabetes

Medical innovation doesn’t mean having to travel thousands of miles to participate in vital research studies. With the power of TrialNet, families can take charge of their health from the comfort of their homes. And research like this is important for everyone to be aware of, regardless of a family history of type 1 diabetes.

Julia Flaherty

April 28, 2025

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Vertex’s VX-264 Clinical Trial Fails to Produce Results & Ends Abruptly

On March 28, 2025, Vertex Pharmaceuticals announced in a press release that its VX-264 clinical trial had been discontinued because it wasn’t producing significant results in participants with type 1 diabetes (T1D).

Ginger Vieira

April 6, 2025

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New Disease-Modifying Therapies that Delay T1D Onset

Whether you’re in the early stages of type 1 diabetes or have been insulin-dependent for twenty-plus years, you may be curious about cutting-edge research with disease-modifying therapies (DMTs), currently pushing boundaries by reducing the disease’s burden and complications.

Erin Poche

March 24, 2025

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Research in China is Curing Type 1 Diabetes with Fat Cells

Scientists have achieved something previously thought impossible: reprogramming a person’s fat cells to produce insulin. This unprecedented procedure, performed in China, allowed a 25-year-old woman with type 1 diabetes (T1D) to become insulin-independent, marking an extraordinary step forward in diabetes research.

Tara Mayo

March 15, 2025

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Denosumab: Another Reason to Screen for T1D

The City of Hope® in Duarte, California, is a top research institute for diabetes clinical trials, including islet cell transplants and drug treatments. One new T1D trial involves denosumab, a drug used for osteoporosis, to protect and support the proliferation of beta cells from the autoimmune attack.

Erin Poche

February 15, 2025

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Sana Biotech’s Cell Therapy without Immunosuppression is a Gamechanger

The cure most T1Ds are waiting for —is working insulin-producing cells without immunotherapy. Sana Biotechnology’s promising new clinical trial has accomplished just that.

Erin Poche

January 26, 2025

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Will These Scientists and Their Cows Help Cure Type 1 Diabetes?

You might find this hard to believe, but it’s true: scientists are working on a groundbreaking therapy to stop the progression of type 1 diabetes using cloned cows!

Ginger Vieira

January 19, 2025

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Vertex T1D Trial VX-880 Moves into Phase III

Vertex Pharmaceuticals announced that the FDA has approved its T1D clinical trial, VX-880, and that it is moving into phase III.

Erin Poche

December 1, 2024

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First T1D Functional Cure Using Immunosuppressive Therapy

In a University of Chicago Medicine clinical trial, two type 1 diabetes patients who received islet cell transplants and immunosuppressive therapy have achieved a “functional cure,” while a third participant’s insulin requirement is down 60% and expected to achieve full insulin independence as well. Eledon Pharmaceuticals’ novel immunosuppression drug, tegoprubart, was used to prevent pancreatic islet cell transplant rejection.

Erin Poche

November 10, 2024

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Stem Cell Therapy to Reverse T1D Inspires Hope

While each new medical advancement raises our hopes, like the recent clinical study from a Chinese Hospital in which a woman’s T1D was ‘reversed,’ it’s important to remember that though it may not be the miracle cure we’re waiting for, each discovery brings us a little closer to the end goal of insulin independence.

Erin Poche

November 4, 2024

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Diamyd Medical has a Clinical Trial for Newly Diagnosed T1Ds

Imagine, as a person with type 1 diabetes, a simple injection that could protect the insulin-producing cells in your pancreas from an immune system attack. Diamyd Medical has invented a drug that does just that.

Ginger Vieira

October 27, 2024

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T1D Human Trials Happening Right Now

We’ve all heard at the time of diagnosis there will be a cure in five years. Five years pass, leaving us wondering if we’ll ever see a practical type 1 diabetes cure in our lifetime. While it’s important to thrive with diabetes, it’s also paramount to see what is on the horizon in diabetes research, particularly human trials happening right now.

Erin Poche

September 1, 2024

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Vertex Pharmaceuticals Seeks Solutions to Cure T1D

If you have type 1 diabetes (T1D) and don’t have Vertex Pharmaceuticals on your radar, it’s high time to follow this leading biotechnology company, which is quickly becoming a pioneer in diabetes research and development.

Erin Poche

January 28, 2024

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Interview with Breakthrough T1D (Formerly JDRF) Market Director, Mike Somers

In an exclusive interview with Breakthrough T1D (Formerly JDRF) Market Director, Mike Somers, he unveils groundbreaking type 1 diabetes research insights and the organization's relentless pursuit of a cure.

T1D Team

November 22, 2023

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Lantidra: A Possible Cure for TID?

Type 1 diabetes communities seek a procedure that produces and protects insulin-producing cells without the health risk of additional drugs throughout the individual’s lifetime. CellTrans is currently working on a microencapsulation procedure to prevent immune rejection, which is optimistic.

Erin Poche

October 24, 2023

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Three Months Later: Katie Beth Hand's Life After Becoming Insulin-Independent in the Eledon Trial

Father and Son Paul and Nick Peloso Discuss Growing Up with Type 1 Diabetes and the Breakthrough T1D Therapy Paul Is Developing

Highlights, Controversy, and Celebration at the ADA’s 86th Scientific Sessions

Tzield Just Approved for Ages 1 and Up in Stage 2 T1D

Type 1 Diabetes Breakthroughs to Watch in 2026

From Screening Her Children to Starting Tzield: Chris Dunn’s Type 1 Diabetes Journey

Think Like a Pancreas: Gary Scheiner on Type 1 Diabetes Education and Living Well

Tegoprubart is a Game Changer in Islet Cell Transplantation Surgery for T1D Patients

Type 1 Diabetes in 2025: Advances in Early Detection, Screening, and What’s Next

Inside the Chicago Diabetes Project: Executive Director Jill Dine on the Search for a T1D Cure

Baricitinib’s Breakthrough and Why Screening for T1D Matters More Than Ever

Catching Type 1 Early: A Mom’s Journey Through Screening and Tzield Therapy

Why More Families Are Screening Their Children for Type 1 Diabetes—Two Stories with Different Outcomes

COUR Pharma Pursues Disease-Modifying Therapy for T1D

What Causes Type 1 Diabetes: Your Beta Cells or Immune System?

Doctors at UI Health Performed the First Islet Transplant with Lantidra

Top Type 1 Diabetes Research Breakthroughs to Watch in 2025

Zucara’s New Drug Aims to Prevent Overnight Lows in Type 1 Diabetes

Diabetes Research Connection Launches 2025 Funding Opportunities for Early-Career Type 1 Diabetes Scientists

T1D Cure Research Breakthroughs from Vertex and Sana Biotechnology

TrialNet Helps Delay the Progression of Type 1 Diabetes

Vertex’s VX-264 Clinical Trial Fails to Produce Results & Ends Abruptly

New Disease-Modifying Therapies that Delay T1D Onset

Research in China is Curing Type 1 Diabetes with Fat Cells

Denosumab: Another Reason to Screen for T1D

Sana Biotech’s Cell Therapy without Immunosuppression is a Gamechanger

Will These Scientists and Their Cows Help Cure Type 1 Diabetes?

Vertex T1D Trial VX-880 Moves into Phase III

First T1D Functional Cure Using Immunosuppressive Therapy

Stem Cell Therapy to Reverse T1D Inspires Hope

Diamyd Medical has a Clinical Trial for Newly Diagnosed T1Ds

T1D Human Trials Happening Right Now

Vertex Pharmaceuticals Seeks Solutions to Cure T1D

Interview with Breakthrough T1D (Formerly JDRF) Market Director, Mike Somers

Lantidra: A Possible Cure for TID?

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